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KMID : 1144320190510010067
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감염과 화학요법
2019 Volume.51 No. 1 p.67 ~ p.72
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Changes in Serotype of Streptococcus pneumoniae After the Introduction of the 13-Valent Pneumococcal Vaccine in a Homogenous Population on Jeju Island
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Yoo Jeong-Rae
Heo Sang-Taek
Oh Hyun-Joo
Oh Su-Hyun
Kim Young-Ree
Lee Keun-Hwa
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Abstract
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We compared the serotypes of Streptococcus pneumoniae between the pre-pneumococcal conjugate vaccine (PCV)13 era and post-PCV13 era among homogenous inhabitants of an isolated South Korean island. A total of 325 S. pneumoniae strains were isolated. In the pre-PCV13 era, 19A/F, 15A/F, 19B, and 23A serotypes were identified. In the post-PCV13 era, 15 serotypes were identified. The 19F and 23A serotypes showed the highest prevalence in the pre- and post-PCV13 era, respectively. After PCV13 introduction, the PCV 13 serotype coverage rate was decreased (80.0% and 30.5% in the pre- and post-PCV13 eras, respectively), while the proportion of non-PCV 13 serotypes increased.
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KEYWORD
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Streptococcus pneumonia, vaccination, PCV 13 vaccine, Jeju Island, Korea
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